Bladder Cancer Information

Bladder cancer is the uncontrolled growth of cells (tumors) within the bladder, a balloon-like organ in the lower abdomen that stores urine produced by the kidneys. Bladder cancer begins in the lining layer and grows into the bladder wall. One of the most common symptoms of bladder cancer is the presence of blood in the urine, which may or may not be accompanied by pain during urination. A urologist can diagnose bladder cancer during a comprehensive, in-office examination, which can include the use of either the NMP22® BladderChek® Test or the NMP22® Test Kit.

Bladder cancer is diagnosed by stage and grade. The stage refers to how advanced a cancer is, while the grade refers to cell appearance and aggressiveness. Stage is determined by the depth to which the tumor has penetrated the bladder wall, and assessment of invasion of lymph nodes and other surrounding organs and tissues. The grade is determined by pathology tests, showing how abnormal the cells of biopsy specimens appear and how closely a tumor resembles normal tissue of its same type.

Types of Bladder Cancer
There are two main types of bladder cancer found in the United States. They are grouped by the way they look under a microscope.

 
Urothelial carcinoma
Squamous cell carcinoma
 
 
This is by far the most common type of bladder cancer. Within this group are also several sub-types depending on their shape and whether or not they tend to spread (invasive).

This type is much less common and is usually invasive.

While there are other types of bladder cancer, they are very rare. There are also a number of bladder tumors that are either benign (not cancer) or not quite cancer.

 

Who Gets Bladder Cancer?
The American Cancer Society estimates that 63,210 new cases of bladder cancer will be diagnosed in the United States during 2005. About 13,180 people will die of the disease. Bladder cancer is almost three times more common among men than women and has almost the same incidence in men as colon cancer. When found and treated early, the chances for survival are very good. However, bladder cancer has a 50 - 80% recurrence rate and therefore must be very closely monitored.

What are the Risk Factors for Bladder Cancer?
The greatest risk factor for bladder cancer is smoking. According to the American Cancer Society, smokers get bladder cancer twice as often as people who do not smoke. Due to the low turnover rate of the cells that line the bladder walls, a smoker’s risk for bladder cancer does not significantly decrease once the person has stopped smoking. There are additional occupational risk factors for bladder cancer associated with a variety of occupations, particularly fire fighters, fire investigators, coalminers, truck drivers and those who work with textiles, rubber, petrochemicals and dyes.

flash